2024
Gianpaolo Maggi, Chiara Giacobbe, Carmine Vitale, Marianna Amboni, Ignacio Obeso & Gabriella Santangelo. Theory of mind in mild cognitive impairment and Parkinson’s disease: The role of memory impairment. CABN 24 (1), 156-170, 2024
G Maggi, F Loayza, C Vitale, G Santangelo, I Obeso. Anatomical correlates of apathy and impulsivity co-occurrence in early Parkinson’s disease. Journal of Neurology, 1-12. 2024
Beatriz Fernández‐Rodríguez, Rafael Rodríguez‐Rojas, Pasqualina Guida, Clara Trompeta, David Mata‐Marín, Ignacio Obeso, … Carmen Gasca‐Salas. Cognitive reserve in Parkinson's disease without dementia: β‐amyloid and metabolic assessment. Movement Disorders Clinical Practice, 2024
Raúl Martínez Fernández, Elena Natera Villalba, ..., Ignacio Obeso, David Mata-Marín, Pasqualina Guida,... Unilateral focused ultrasound subthalamotomy in early Parkinson’s disease: a pilot study. Journal of Neurology, Neurosurgery & Psychiatry 95 (3), 206-213. 2024
2023
Alfonsina D’Iorio, Gianpaolo Maggi, Pasqualina Guida, Edoardo Nicolò Aiello, Barbara Poletti, Vincenzo Silani, Nicola Ticozzi, Gabriella Santangelo, Ignacio Obeso. Early Detection of Depression in Parkinson’s Disease: Psychometrics and Diagnostics of the Spanish Version of the Beck Depression Inventory. Archives of Clinical Neuropsychology, 2023
David Mata-Marín, Peter Redgrave, Ignacio Obeso. The Impact of Emotions on Habitual Inhibition. Journal of Cognitive Neuroscience. Nov 2023
J Caballero-Insaurriaga, JA Pineda-Pardo, I Obeso, A Oliviero, G Foffani. Noninvasive modulation of human corticostriatal activity. Proceedings of the National Academy of Sciences, 2023; 120 (15), e2219693120
Brain hypometabolism in non-demented microtubule-associated protein tau H1 carriers with Parkinson's disease Carmen Gasca-Salas, Clara Trompeta, Miguel López-Aguirre, Rafael Rodríguez Rojas, Jordi Clarimon, Oriol Dols-Icardo, Shaimaa El Bounasri, Pasqualina Guida, David Mata-Marín, Frida Hernández-Fernández, Connie Marras, Lina García-Cañamaque, Isabel Plaza de las Heras, Ignacio Obeso, Lydia Vela, Beatriz Fernández-Rodríguez. Journal of Neuroimaging. September 2023
Longitudinal assessment of social cognition in de novo Parkinson’s disease patients and its relationship with dopaminergic innervation. Clara Trompeta, Carmen Gasca-Salas, José A. Pineda-Pardo, Pasqualina Guida, Melanie Cohn, David Mata-Marín, Mariana HG Monje, Miguel López-Aguirre, Ignacio Obeso, Álvaro Sánchez Ferro. Behavioural Brain Research. Volume 454, 2 October 2023, 114654
David Mata-Marín, José Ángel Pineda-Pardo, Mario Michiels, Cristina Pagge, Claudia Ammann, Raúl Martínez-Fernández, José Antonio Molina, Lydia Vela-Desojo, Fernando Alonso-Frech, Ignacio Obeso. A circuit-based approach to modulate hypersexuality in Parkinson’s disease. Psychiatry & Clinical Neuroscience. 2023
Prospective Long-term Follow-up of Focused Ultrasound Unilateral Subthalamotomy for Parkinson´s Disease. Martinez-Fernandez R, Natera-Villalba E, Máñez Miró JU, Rodriguez-Rojas R, Marta Del Álamo M, Pineda-Pardo JÁ, Ammann C, Obeso I, Mata-Marín D, Hernández-Fernández F, Gasca-Salas C, Matarazzo M, Alonso-Frech F, Obeso JA. Neurology. 2023 Jan 11
2022
Guida P, Foffani G, Obeso I. The supplementary motor area and automatic cognitive control: lack of evidence from two neuromodulation techniques. J Cognitive Neurosci 2022. Dec 28;1-13
G Maggi, D Di Meglio, C Vitale, M Amboni, I Obeso, G Santangelo. The impact of executive dysfunctions on Theory of Mind abilities in Parkinson's disease. Neuropsychologia, 2022
JA Pineda‐Pardo, C Gasca‐Salas, B Fernández-Rodríguez, ...I Obeso... Striatal Blood–Brain Barrier Opening in Parkinson's Disease Dementia: A Pilot Exploratory Study. Movement Disorders 2022
Guida P, Michiels M, Redgrave P, Luque D, Obeso I. An fMRI meta-analysis of the role of the striatum ineveryday-life vs laboratory-developed habits. Neurosci Biobehav Rev. 2022 Aug 10
Gianpaolo Maggi, Amable Manuel Cima Muñoz, Ignacio Obeso, Gabriella Santangelo. Neuropsychological, neuropsychiatric, and clinical correlates of affective and cognitive theory of mind in Parkinson's disease: A meta-analysis. Neuropsychology. 2022 Apr 7.
David Mata-Marin,Jose Angel Pineda-Pardo, Mario Michiels, Cristina Pagge, Claudia Ammann, Raul Martinez-Fernandez, Jose Antonio Molina, Lydia Vela-Desojo, Fernando Alonso-Frech, Ignacio Obeso. A circuit-based approach to repair hypersexuality in Parkinson's disease medRxiv
Francis R. Loayza, Ignacio Obeso, Rafael González Redondo, Federico Villagra, Elkin Luis, José A. Obeso, Marjan Jahanshahi & Maria A. Pastor. The motor inhibitory network in patients with asymmetrical Parkinson’s disease: An fMRI study. Brain Imaging and behaviour
2021
Pasqualina Guida, Mario Michiels, Peter Redgrave, David Luque, Ignacio Obeso. Striatal role in everyday-life and laboratory-developed habits. BioRXiv
D’Iorio A, Pasqualina Guida, Maggi G, Redgrave P, Santangelo G, Obeso I. Neuropsychological spectrum in early PD: insights from controlled and automatic behavioural regulation. Neuroscience and Biobehavioral Reviews. Volume 126, 465-480. 2021
Mata-Marín D, Pineda-Pardo J.A., Molina J.A., Vela L, Alonso F, Obeso I. Aberrant salient and corticolimbic connectivity in hypersexual Parkinson’s disease. Brain Connectivity. 2021. 17 May.
Ignacio Obeso, Maria-Trinidad Herrero, Romain Ligneul, John C.Rothwell, Marjan Jahanshahi. A Causal Role for the Right Dorsolateral Prefrontal Cortex in Avoidance of Risky Choices and Making Advantageous Selections. Neuroscience Volume 458, 15 March 2021, Pages 166-179. 2021
Gasca-Salas C, Fernández-Rodríguez B, Pineda-Pardo J, Rodríguez-Rojas R, , Hernández-Fernandez F, del Álamo M, Mata-Marín D, Guida P, Ordás-Bandera C, Montero Roblas JI, Martínez-Fernández R, Foffani G, Rachmilevitch I, Obeso J. Blood-Brain Barrier Opening with Focused Ultrasound in Parkinson´s Disease Dementia: A Safety and Feasibility Study. Nature Communications 2021
2020
Martínez-Fernández R, Máñez-Miró JU, Rodríguez-Rojas R, Del Álamo M, Shah BB, Hernández-Fernández F, Pineda-Pardo JA, Monje MHG, Fernández-Rodríguez B, Sperling SA, Mata-Marín D, Guida P, Alonso-Frech F, Obeso I, Gasca-Salas C, Vela-Desojo L, Elias WJ, Obeso JA. Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson's Disease. N Engl J Med. 2020
Chen G, Li Y, Dong Z, Wang R, Zhao D, , Yu S. Response inhibition alterations in migraine: evidence from event-related potentials and evoked oscillations. J Headache and Pain. 2020
Li Y, Météreau E, Butera L, Villeval MC, Dreher JC. Endogenous testosterone is associated with increased striatal response to audience effects during prosocial choices. Psychoneuroendocrinology 2020
Ammann C, Dileone M, Pagge C, Catanzaro V, Mata-Marín D, Hernández-Fernández F, Monje MHG, Sánchez-Ferro Á, Fernández-Rodríguez B, Gasca-Salas C, Máñez-Miró JU, Martínez-Fernández R, Vela-Desojo L, Alonso-Frech F, Oliviero A, Obeso JA, Foffani G. Cortical disinhibition in Parkinson's disease. Brain. 2020 Dec 5;143(11):3408-3421
Ammann, C, Guida P, Caballero-Insaurriaga J, Pineda-Pardo J, Oliviero A, Foffani G. A framework to assess the impact of number of trials on the amplitude of motor evoked potentials. Scientific Reports, 2020. 10(1), 1–15.
Wang Z, Zhang X, Liu R, Wang Y, Qing Z, Lu J, Obeso I, Zhang B, Li Y. Altered sulcogyral patterns of orbitofrontal cortex in patients with mild cognitive impairment. Psychiatry Res Neuroimaging 2020
Williams I, Obeso I, Jahanshahi M. Dopaminergic medication improves cognitive control under low cognitive demand in Parkinson’s disease. Neuropsychologia 2020
Altimus CM, Marlin BJ, Charalambakis NE, Colón-Rodriquez A, Glover EJ, Izbicki P, Johnson A, Lourenco M V, Makinson RA, McQuail J, Obeso I, Padilla-Coreano N, Wells MF, for Training Advisory Committee. The Next 50 Years of Neuroscience. J Neurosci 40:101–106. 2020.
2019
Pineda-Pardo J*, Obeso I*, Guida P, Dileone M, Strange BA, Obeso JA, Oliviero A, Foffani G. Static magnetic field stimulation of the supplementary motor area modulates resting-state activity and motor behavior. Nat Comm Biol 2019.
Hernández LF, Obeso I, Costa RM, Redgrave P, Obeso JA. Dopaminergic Vulnerability in Parkinson Disease: The Cost of Humans’ Habitual Performance. Trends in Neuroscience. 2019.
Gasca-Salas C, Guida P, Piredda R, Obeso I,Vela Desojo L, Martínez-Fernández R, Hernández-Fernández F, Máñez-Miró J, Pineda-Pardo JA, Del Álamo M, Rodriguez-Rojas R, Mata-Marín D, Alonso-Frech F, de Luis E, Obeso JA. Cognitive safety after unilateral magnetic resonance-guided focused ultrasound thalamotomy for essential tremor. J Neurol Neurosurg Psychiatry. 2019 Mar 8.
Girard G*, Obeso I,* Thobois S, Park SA, Vidal T, Favre E, Ulla M, Broussolle E, Krack P, Durif F, Dreher JC. Wait and you shall see: sexual delay discounting in hypersexual Parkinson’s disease. Brain. 2019. Jan 1;142(1):146-162. * Co-first aurthor.
Pytel V, Montero P, Mejías G, Delgado-Álvarez A, Moreno-Ramos T, Matías-Guiu J, Matías-Guiu JA. Repetitive transcranial magnetic stimulation in a case of atypical parkinsonism. Brain Stimul. 2019 Sep-Oct;12(5):1343-1344
Mejías G, Prieto J. A single case report of a patient with stuttering who improved after open label TMS. Brain Stimul. 2019 May-Jun;12(3):785-786.
Matarazzo M, Arroyo-Gallego T, Montero P, Puertas-Martín V, Butterworth I, Mendoza CS, Ledesma-Carbayo MJ, Catalán MJ, Molina JA, Bermejo-Pareja F, Martínez-Castrillo JC, López-Manzanares L, Alonso-Cánovas A, Rodríguez JH, Obeso I, Martínez-Martín P, Martínez-Ávila JC, de la Cámara AG, Gray M, Obeso JA, Giancardo L, Sánchez-Ferro Á. Remote Monitoring of Treatment Response in Parkinson's Disease: The Habit of Typing on a Computer. Mov Disord. 2019.
2018
Obeso I, Moisa M, Ruff CC, Dreher J-C. A causal role for right temporo-parietal junction in signaling moral conflict. Elife. 2018.
Pereira AM, Campos BM, Coan AC, Pegoraro LF, de Rezende TJR, Obeso I, Dalgalarrondo P, da Costa JC, Dreher JC, Cendes F. Differences in Cortical Structure and Functional MRI Connectivity in High Functioning Autism. Front Neurol. 2018 Jul 10;9:539.
Martínez-Fernández R, Rodríguez-Rojas R, Del Álamo M, Hernández-Fernández F, Pineda-Pardo JA, Dileone M, Alonso-Frech F, Foffani G, Obeso I, Gasca-Salas C, de Luis-Pastor E, Vela L, Obeso JA. Focused ultrasound subthalamotomy in patients with asymmetric Parkinson's disease: a pilot study. Lancet Neurol. 2018 Jan;17(1):54-63.
Mejías G, Oliviero A, Barcia JA, Nombela C. Stuttering and levetiracetam: Case report and research proposal. Ann Clin Psychiatry. 2018 Feb;30(1):68-69.
2017
Obeso I, Casabona E, Rodríguez-Rojas R, Bringas ML, Macías R, Pavón N, Obeso JA, Jahanshahi M. Unilateral subthalamotomy in Parkinson's disease: Cognitive, psychiatric and neuroimaging changes. Cortex. 2017 Sep;94:39-48.
Obeso I, Wilkinson L, Teo JT, Talelli P, Rothwell JC, Jahanshahi M. Theta burst magnetic stimulation over the pre-supplementary motor area improves motor inhibition. Brain Stimul. 2017 Sep - Oct;10(5):944-951.
Cerasa A, Obeso I, Dileone M, Quattrone A. Transcranial Non-Invasive Brain Stimulation in Parkinson's Disease Patients with Dyskinesias. Where is the Optimal Target? Cerebellum. 2017 Feb;16(1):276-278.
Strafella AP, Bohnen NI, Perlmutter JS, Eidelberg D, Pavese N, Van Eimeren T, Piccini P, Politis M, Thobois S, Ceravolo R, Higuchi M, Kaasinen V, Masellis M, Peralta MC, Obeso I, Pineda-Pardo JÁ, Cilia R, Ballanger B, Niethammer M, Stoessl JA; IPMDS-Neuroimaging Study Group. Molecular imaging to track Parkinson's disease and atypical parkinsonisms: New imaging frontiers. Mov Disord. 2017 Feb;32(2):181-192.
2016
Ligneul R, Obeso I, Ruff C.C., Dreher J.C. Dynamical Representation of Dominance Relationships in the Human Rostromedial Prefrontal Cortex. Current Biology, Volume 26, Issue 23, 5 December 2016, Pages 3107–3115. 3.
Obeso I, Oliviero A, Jahanshahi M. Editorial: Non-invasive Brain Stimulation in Neurology and Psychiatry. Front Neurosci. 2016 Dec 15;10:574. Editorial & Full eBook
Hernández LF, Obeso I. A STOP signal to striatum mediated by globus pallidus: A new loop discovered. Mov Disord. 2016 Apr 19.
2015
Obeso I, Cerasa A, Quattrone A. The Effectiveness of Transcranial Brain Stimulation in Improving Clinical Signs of Hyperkinetic Movement Disorders. Front Neurosci. 2016 Jan 7;9:486. eCollection 2015.
Kohl S, Aggeli K, Obeso I, Speekenbrink M, Limousin P, Kuhn J, Jahanshahi M. In Parkinson's disease pallidal deep brain stimulation speeds up response initiation but has no effect on reactive inhibition. J Neurol. 2015 Jul;262(7):1741-50.
Jahanshahi M, Obeso I, Rothwell J, Obeso JA. A striato-subthalamic-frontal mechanism for goal-directed and habitual inhibition. Nature Reviews Neuroscience. 2015 Dec;16(12):719-32.
Abi-Jaoude E, Segura B, Obeso I, Cho SS, Houle S, Lang AE, Rusjan P, Sandor P, Strafella AP. Similar striatal D2/D3 dopamine receptor availability in adults with Tourette syndrome compared with healthy controls: A [11 C]-(+)-PHNO and [11 C]raclopride positron emission tomography imaging study. Human Brain Mapping. 2015 Mar 18.
Jahanshahi M, Obeso I, Baunez C, Alegre M, Krack P. Parkinson's Disease, the Subthalamic Nucleus, Inhibition, and Impulsivity. Mov Disord. 2015 Feb;30(2):128-40.
Cho SS, Koshimori Y, Aminian K, Obeso I, Rusjan P, Lang AE, Daskalakis ZJ, Houle S, Strafella AP. Investing in the Future: Stimulation of the Medial Prefrontal Cortex Reduces Discounting of Delayed Rewards. Neuropsychopharmacology. 2015 Feb;40(3):546-53.
2014
Obeso I, Wilkinson L, Casabona E, Speekenbrink M, Bringas M.L, Alvarez M, Alvarez L, Pavon N, Rodríguez-Oroz M.C., Macías R, Obeso J.A. and Jahanshahi M. The subthalamic nucleus and inhibitory control: impact of subthalamotomy in Parkinson’s disease. Brain. 2014; May;137(Pt 5):1470-80.
Obeso I and Strafella AP. Top-down Control of Dyskinesias in PD Using Brain Stimulation. Brain Stimulation. 2014; May-Jun;7(3):488.
Osman M, Ryterska A, Karimi K, Tu L, Obeso I, Speekenbrink M, Jahanshahi M. The effects of dopaminergic medication on dynamic decision making in Parkinson's disease. Neuropsychologia. 2014; Jan;53:157-64.
Obeso I and Strafella AP. Boosting Response Inhibition Neural Network With rTMS May Improve Dyskinesias in Parkinson's Disease. Brain Stimulation. 2014; Mar-Apr;7(2):336-7.
2013
Obeso I, Robles N, Muñoz‐Marrón E and Redolar‐Ripoll D. Dissociating the role of the pre-SMA in response inhibition and switching: a combined online and offline TMS approach. Front. Hum. Neurosci. 2013; 7:150.
Obeso I, Cho S.S., Antonelli F, Houle S, Jahanshahi M, Ko J.H and Strafella AP. Stimulation of the pre-SMA influences cerebral blood flow in frontal areas involved with inhibitory control of action. Brain Stimulation. 2013; Sep;6(5):769-76.
Obeso I, Wilkinson L, Rodríguez-Oroz M.C, Obeso J.A., and Jahanshahi M. Bilateral stimulation of the subthalamic nucleus has differential effects on reactive and proactive inhibition and conflict-induced slowing in Parkinson's disease. Exp Brain Res.2013; May;226(3):451-62.
Alegre M, Lopez-Azcarate J, Obeso I, Wilkinson L, Rodriguez-Oroz M.C, Valencia M, Garcia-Garcia D, Guridi J, Artieda J, Jahanshahi M, Obeso J.A. The subthalamic nucleus is involved in successful inhibition in the stop-signal task: A local field potential study in Parkinson's disease. Exp Neurol. 2013; Jan;239:1-12.
2012
Cho SS, Pellecchia G, Aminian K, Ray N, Segura B, Obeso I, Strafella AP. Morphometric Correlation of Impulsivity in Medial Prefrontal Cortex. Brain Topogr. 2012; Dec 30.
Cho S.S., Pellechia G, Ko J.H., Ray N, Obeso I, Sylvain H, Strafella AP. Effect of continuous theta burst stimulation of the right dorsolateral prefrontal cortex on cerebral blood flow changes during decision making. Brain Stimulation. 2012; Apr;5(2):116-23.
Obeso I, Casabona E, Bringas M.L., Alvarez L, and Jahanshahi M. Semantic and phonemic verbal fluency in Parkinson’s disease: influence of clinical and demographic variables. Behavioral Neurology. 2012; 25(2):111-118.
2011
Obeso I, Ray N, Antonelli F, Cho S.S., Strafella AP. Combining functional imaging with brain stimulation in Parkinson’s disease. International Review of Psychiatry. 2011; October; 23(5): 467–475.
Obeso I, Wilkinson L, Casabona E, Bringas M.L., Alvarez M, Rodríguez-Oroz M.C., Pavon N, Alvarez L, Macías R, Obeso J.A., and Jahanshahi M. Deficits in inhibitory control and conflict resolution in cognitive and motor tasks in Parkinson’s disease. Exp Brain Res. 2011; 212(3): 371-84.
Obeso I, Wilkinson L, Jahanshahi M. The effect of Levodopa on inhibition and response initiation under conflict in Parkinson’s disease. Exp Brain Res. 2011; 213(4): 435-45.
2010
Wilkinson W, Teo J, Obeso I, Talelli P, Rothwell J, Jahanshahi M. The Contribution of Primary Motor Cortex is Essential for Probabilistic Implicit Sequence Learning: Evidence from Theta Burst Magnetic Stimulation. J Cognitive Neurosci. 2011; Mar;22(3):427-36.